Product Name : Apixaban

CAS : 503612-47-3

Molecular Formula : C25H25N5O4

Molecular Weight : 459.5 g/mol

Pharmaceutical Grade :

Therapeutic Category : Anticoagulant


Global Calcium is one of the leading manufacturers and exporters of Apixaban CAS no. 503612-47-3, API, (Active Pharmaceutical Ingredient). We support the customers with exhaustive documentation. As a USDMF & EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979.

As manufacturer of Apixaban we hereby state the following facts about the drug:

Apixaban is a direct factor Xa (FXa) inhibitor that is used to prevent blood clots in people with atrial fibrillation (AF), deep vein thrombosis (DVT), and pulmonary embolism (PE). It is also used to treat DVT and PE.

Indications for Apixaban

  • Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
  • Prophylaxis of deep vein thrombosis (DVT) leading to pulmonary embolism (PE) in patients after a hip or knee replacement surgery.
  • Treatment of DVT and PE to reduce the risk of recurrence.

Mechanism of action of Apixaban

Apixaban works by blocking the action of factor Xa, a protein that plays a key role in the blood clotting cascade. By blocking factor Xa, Apixaban prevents the formation of blood clots.

Apixaban is a highly selective inhibitor of factor Xa, meaning that it has little effect on other proteins in the blood clotting cascade.

Global Calcium is a leading manufacturer of this drug. We manufacture this pharmaceutical drug and make it available to domestic and overseas market