Product Name : Etifoxine

CAS : 21715-46-8

Molecular Formula : C17H17ClN2O

Molecular Weight : 300.8 g/mol

Pharmaceutical Grade :

Therapeutic Category : Anxiolytic agent


Global Calcium is one of the leading manufacturers and exporters of Etifoxine CAS no. 21715-46-8, API, (Active Pharmaceutical Ingredient). We support the customers with exhaustive documentation. As a USDMF & EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979.

As manufacturer of Etifoxine we hereby state the following facts about the drug:

Etifoxine, a well-established anxiolytic and anticonvulsant compound, stands as a pivotal agent known for its therapeutic benefits in anxiety disorders and neuroprotection. As a trusted pharmaceutical ingredient, etifoxine has garnered attention for its unique mechanism of action and its efficacy in addressing various neurological conditions.

Mechanism of Action: Etifoxine's mode of action involves multiple pathways within the central nervous system. Unlike traditional anxiolytics, it acts through a dual mechanism, primarily targeting GABAergic neurotransmission by potentiating GABA (gamma-aminobutyric acid) action. This action enhances GABAergic inhibitory neurotransmission, leading to a calming effect without inducing sedation or cognitive impairment. Additionally, etifoxine has been shown to modulate translocator protein (TSPO), exhibiting neuroprotective and anti-inflammatory properties that contribute to its therapeutic benefits in neurological disorders.


  • Anxiety Disorders: Etifoxine has demonstrated efficacy in managing generalized anxiety disorders (GAD) and situational anxiety, offering relief from symptoms without causing significant sedation.
  • Neuroprotection: Its neuroprotective properties make etifoxine a promising agent for various neurodegenerative conditions, potentially alleviating oxidative stress, neuroinflammation, and promoting neuronal survival and function.

Global Calcium is a leading manufacturer of this drug. We manufacture this pharmaceutical drug and make it available to domestic and overseas market