Metopimazine IH

Global Calcium is one of the leading manufacturers and exporters of Metopimazine CAS no. 14008-44-7, API, (Active Pharmaceutical Ingredient). We support the customers with exhaustive documentation. As a USDMF & EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979.

As manufacturer of Metopimazine we hereby state the following facts about the drug:

Indications for Use

Used in the prevention of delayed chemotherapy induced nausea and vomiting (CINV) following moderately and as add-on therapy in refractory cases.

Mechanism of Action

Metopimazine is a phenothiazine derivative with anti domaminergic activity. It has a high affinity for dopamine D2 receptors (and also α- adrenoreceptors and histamine H1 receptors). But no affinity for serotonin 5-HT3 receptors. It exerts its antiemetic effect via the chemoreceptor trigger zone.

Global Calcium is a leading manufacturer of this drug. We manufacture this pharmaceutical drug and make it available to domestic and overseas market