Product Name : Midazolam
CAS : 59467-70-8
Molecular Formula : C18H13ClFN3
Molecular Weight : 325.8 g/mol
Pharmaceutical Grade : BP / EP / IP / USP
Therapeutic Category : Anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic
Global Calcium is one of the leading manufacturers and exporters of Midazolam CAS no. 59467-70-8, API, (Active Pharmaceutical Ingredient). We support the customers with exhaustive documentation. As a USDMF & EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979.
As manufacturer of Midazolam we hereby state the following facts about the drug:
Midazolam is a short-acting benzodiazepine derivative with an imidazole structure and with anxiolytic, amnestic, hypnotic, anticonvulsant, and sedative properties. Midazolam exerts its effect by binding to the benzodiazepine receptor at the gamma-aminobutyric acid (GABA) receptor-chloride ionophore complex in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA in the CNS. Midazolam may also interfere with the reuptake of GABA, thereby causing the accumulation of GABA in the synaptic cleft
Midazolam has neurotoxic properties when administered neuraxial in vivo. Furthermore, midazolam induces neurodegeneration in neonatal animal models in combination with other general anesthetics.
Therapeutic uses and effectiveness:
Global Calcium is a leading manufacturer of this drug. We manufacture this pharmaceutical drug and make it available to domestic and overseas market